Platelet Rich Plasma (PRP)

What is PRP?


Platelet-rich plasma (PRP) is a treatment that uses your body's own blood to help heal injuries and reduce pain. Platelets are cells that promote healing. In PRP therapy, a small sample of your blood is drawn and placed in a machine that concentrates it down to platelets which are then injected into the injured or painful area.

Indications

PRP therapy is commonly used for

  • Knee osteoarthritis

  • Lateral epicondylitis (Tennis Elbow)

  • Plantar fasciitis

  • Tendon injuries

  • Ligament injuries

Before the Procedure

Stop anti-inflammatory medications (NSAIDS) such as ibuprofen (Advil), naproxen (Aleve), or aspirin at least 7 days before your procedure.

  • These medications can interfere with how platelets work and reduce the effectiveness of PRP.

If you have recieved a steroid injection or take oral steroids, let your doctor know. When possible, steroids should be stopped at least 2 weeks before a PRP procedure.

During the Procedure

PRP is done in the office as a same-day, outpatient procedure.

  • Some blood will be taken from your arm.

  • The blood is then placed in a centrifuge and spun to concentrate the platelets.

  • The platelet rich plasma is then drawn into a syringe.

  • The injection site may then be cleaned and injected with a local anesthetic.

  • The platelet rich plasma is injected into the effected area, sometimes with an ultrasound for guidance.

This procedure generally takes 30-45 minutes.

Post Procedure

It is normal to have some soreness, redness, or mild swelling at the treatment site. These are signs that your body’s healing response has been activated. These symptoms are temporary and should go away in a few days.

Medication Guidelines

  • Do not take anti-inflammatory medications (NSAIDS) like ibuprophen (Advil), naproxen (Aleve), aspirin, or diclofenac (Voltaren) for at least 2 weeks following treatment.

  • Acetaminophen (Tylenol) is safe to take if needed for pain relief.

  • Ice packs may be applied to the treated area

Activity Guidelines

  • Days 1–2: Rest the treated area. Avoid heavy, repetitive, or strenuous activity involving the injection site. Light daily activities (walking, gentle movement) are generally fine.

  • Days 3–7: You may begin gentle stretching of the treated area as tolerated. Continue to avoid vigorous exercise, running, heavy lifting, or sports.

  • Weeks 2–3: You may begin light strengthening exercises as directed by your provider or physical therapist.

  • Weeks 4–6: Gradual return to full activity and sports, based on your symptoms and your provider's guidance.

PRP does not provide instant relief. It works by jumpstarting your body’s natural healing process. Most patients see improvements in pain and function about 6 weeks after the injection.

When to call your doctor

Contact your doctor if you experience any of the following after the procedure

  • Fever or chills

  • Severe or worsening pain

  • New weakness or numbness in your arms or legs

  • Difficulty with bowel or bladder control

  • Redness, swelling, or drainage at the injection site

Frequently Asked Questions

  • Improvement is typically gradual, as PRP relies on your body’s natural healing process. Many patients begin noticing changes within a few weeks, with continued improvement over 2-3 months.

  • This depends on the treatment area and your specific condition. Your doctor will provide guidance specific to your recovery.

  • No, avoid taking anti-inflammatory medications such as Advil during the course of your treatment. Tylenol can be used as needed for pain relief.